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Table 4 Breast cancer risk genome-wide association studies using populations of European descent

From: Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci

GWAS

Population

Stages

Cases/controls stage 1

Cases/controls stage 2

Cases/controls stage 3

Cases/controls stage 4

Study P-value cut-off for significance

Ahmed et al. [32]

European descent

4

390/364

3,990/3,928

3,878/3,928

33,134/36,141

P < E-07

Antoniou et al. [33]

European descent

2

1,193/1,190

5,986/2,974

  

P < E-07

Easton et al. [34]

European descent

3

408/400

3,990/3,916

21,860/22,578

 

P < E-07

Fletcher et al. [35]

European descent

3

3,981/2,365

4,804/3,936

4,237/5,044

 

-

Garcia-Closas et al. [36]

European descent

2

4,193/35,194

6,514/41,455

  

P < 5E-08

Gaudet et al. [37]

European descent

2

899/804

1,264/1,222

  

P < E-05

Ghoussaini et al. [38]

European descent

2

56,989/58,098

69,564/68,150

  

P < E-04

Haiman et al. [39]

European descent/African descent

2

African descent (1,004/2,745), European descent (1,718/3,670)

European descent (2,292/16,901)

  

-

Hunter et al. [40]

European descent

2

1,145/1,142

1,776/2,072

  

P < 2E-05

Li et al. [41]

European descent

2

617/4,583

1,011/7,604

  

P < E-05

Li et al. [42]

European descent

2

2,702/ 5,726

?

  

P < E-06

Mavaddat et al. [43]

European descent

2

4,470/4,560

?

  

P < 5E-02/6.25E-03

Michailidou et al. [44]

European descent

2

10,052/12,575

45,290/41,880

  

P < 5E-08

Murabito et al. [45]

European descent

1

250/1,345

   

P < 5E-08

Sehrawat et al. [46]

European descent

2

348/348

1,153/1,215

  

P < 6.4E-08

Stacey et al. [47]

European descent

2

1,600/11,563

4,554/17,577

  

P < E-07/P < 6.8E-08

Stacey et al. [48]

European descent

2

6,145/33,016

5,028/32,090

  

-

Thomas et al. [49]

European descent

3

1,145/1,142

4,547/4,434

4,078/5,223

 

P < 5E-07

Turnbull et al. [50]

European descent

2

3,659/4,897

12,576/12,223

  

P < E-04

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Breast Cancer Research

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