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Table 4 Effect modification of an association a between breast cancer and exposure variables by age and mammographic density in 13,572 women

From: Birth weight, childhood body mass index, and height in relation to mammographic density and breast cancer: a register-based cohort study

  Breast cancer N(%) Birth weight HR (95% CI) BMI at age 13 HR (95% CI) Height at age 13 HR (95% CI)
Age at BC diagnoses (years)     
50-59 years 193 (27.0) 1.01 (0.75-1.36) 1.03 (0.88-1.22) 1.06 (0.92-1.23)
60+ years 523 (73.0) 0.82 (0.66-1.02) 1.00 (0.90-1.11) 1.10 (1.00-1.20)
P value for interaction   0.31 0.81 0.69
Mammographic density     
Mixed/dense breasts 541 (75.5) 0.88 (0.72-1.07) 1.02 (0.92-1.14) 1.13 (1.03-1.23)
Fatty breasts 175 (24.4) 0.92 (0.62-1.36) 1.00 (0.81-1.17) 0.97 (0.83-1.13)
P value for interaction   0.85 0.70 0.08
Total 716 0.89 (0.75-1.06) 1.01 (0.93-1.11) 1.09 (1.01-1.17)
  1. CI, confidence interval; HR, hazard ratio; aAdjusted for age (underlying time scale) and mammographic density, and stratified by birth cohort (1930 to 1934, 1935 to 1939, 1940 to 1944, 1945 to 1949).