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Table 3 Distribution of tumor phenotypes among screening-detected cancers (n = 1,297) and categories of interval cancers (n = 948)

From: Tumor phenotype and breast density in distinct categories of interval cancer: results of population-based mammography screening in Spain

  Screening-detected cancers True interval cancers False negatives Minimal-sign cancers Occult tumors  
  n = 1,297 n = 455 n = 224 n = 166 n = 103 (%) P value
Tumor phenotype       
Luminal A 629 (68.3) 197 (50.9)* 124 (68.1) 79 (59.4) 62 (79.5)  
Luminal B 139 (15.1) 60 (15.5) 29 (15.9) 18 (13.5) 8 (10.3)  
HER2 62 (6.7) 53 (13.7)* 14 (7.7) 13 (9.8) 3 (3.8)  
Triple-negative 91 (9.9)* 77 (19.9)* 15 (8.2) 23 (17.3) 5 (6.4) <0.001
Unknown 376 68 42 33 25  
  1. Results are expressed as number (%). Tumor phenotype = Luminal A (ER+/HER2- or PR+/HER2-); Luminal B (ER+/HER2+ or PR+/HER2+); HER2 (ER-/PR-/HER2+); Triple-negative (ER-/PR-/HER2-). *Standardized Pearson residuals with statistically significant deviation between observed and expected values. The distribution of tumor phenotype was compared among the study groups using the two-sided Chi-square test. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.