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Figure 6 | Breast Cancer Research

Figure 6

From: Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Figure 6

Overlap between methylation and gene expression alterations in the TAMRand LCC cell line models. (A) Venn diagram showing the overlapping number of genes that exhibited altered expression (twofold change) in both the TAMR versus MCF-7/S0.5 and the LCC2 versus LCC1 cell line models. (B) Venn diagram showing the overlapping number of genes that exhibit altered promoter CpG island (CGI) DNA methylation (twofold change) and concurrent inversely altered gene expression (twofold change) in both the TAMR versus MCF-7/S0.5 and the LCC2 versus LCC1 cell line models.

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