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Figure 2 | Breast Cancer Research

Figure 2

From: Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Figure 2

Principle component analysis and unsupervised cluster analysis for DNA methylation and gene expression data in TAMRand MCF-7/S0.5 cell lines. Principle component analysis results for modified DNA methylation-specific digital karyotyping (MMSDK) (A) and digital gene expression (DGE) (B) data show that the TAMR cell lines grouped separately from the parental MCF-7/S0.5 cell line. The unsupervised cluster analyses of MMSDK (C) and DGE (D) also show clear separation of TAMR cell lines from the MCF-7/S0.5 cell line.

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