Table 1 Pathway enrichment analysis of candidate genes
From: A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype
KEGG pathway | Fold enrichment | P-value |
|---|---|---|
A | ||
hsa03050:Proteasome | 3.38 | 1.41E-08 |
hsa03010:Ribosome | 3.89 | 2.28E-06 |
hsa04114:Oocyte meiosis | 1.77 | 1.64E-03 |
hsa04914:Progesterone-mediated oocyte maturation | 1.71 | 5.03E-03 |
hsa03040:Spliceosome | 2.39 | 8.61E-03 |
hsa05110:Vibrio cholerae infection | 1.86 | 1.55E-02 |
hsa04110:Cell cycle | 1.49 | 1.76E-02 |
hsa05016:Huntington’s disease | 1.49 | 1.76E-02 |
hsa03020:RNA polymerase | 2.27 | 1.96E-02 |
hsa00970:Aminoacyl-tRNA biosynthesis | 1.97 | 2.08E-02 |
hsa00730:Thiamine metabolism | 3.57 | 3.30E-02 |
hsa04260:Cardiac muscle contraction | 1.96 | 3.80E-02 |
hsa00240:Pyrimidine metabolism | 1.52 | 4.51E-02 |
hsa00020:Citrate cycle (TCA cycle) | 1.90 | 4.80E-02 |
B | ||
hsa04630:Jak-STAT signaling pathway | 2.05 | 1.76E-03 |
hsa04060:Cytokine-cytokine receptor interaction | 1.67 | 7.08E-03 |
hsa05215:Prostate cancer | 2.22 | 8.50E-03 |
hsa04150:mTOR signaling pathway | 2.72 | 1.47E-02 |
hsa05223:Non-small cell lung cancer | 2.49 | 1.61E-02 |
hsa05200:Pathways in cancer | 1.48 | 1.96E-02 |
hsa04510:Focal adhesion | 1.70 | 2.22E-02 |
hsa04062:Chemokine signaling pathway | 1.63 | 3.91E-02 |
hsa05216:Thyroid cancer | 3.04 | 4.16E-02 |
hsa04640:Hematopoietic cell lineage | 1.88 | 4.97E-02 |