Figure 3

Prognostic performance of the IR-7 and Buck-4 indices in the FFPE cohort. (A) Kaplan-Meier curves of pooled cohort dichotomized at median Buck-4 index value, (B) Kaplan-Meier curves of pooled cohort dichotomized at median IR-7 index value, (C) rpart tree showing that nodal status, IR-7 index and grade were selected in a conditional model which best predicts DR-free status. (D) Kaplan-Meier curves corresponding to branches of the rpart tree. Color of the curves corresponds to terminal branch color: red = node-positive; skyblue = node-negative, high IR-7 index; blue = node-negative, low IR-7 index, grade III; dark blue = node negative, low IR-7 index, grade I/II.