Variable | HR | 95% CI | P b |
---|---|---|---|
Tumor size, cm | |||
<2 | 1.0 | ||
2 to 5 | 1.6 | 1.2 to 2.1 | 0.0003 |
>5 | 2.0 | 1.2 to 3.2 | 0.005 |
Lymph nodes | |||
0 | 1.0 | ||
1 to 3 | 1.4 | 1.0 to 1.8 | 0.01 |
≥4 | 2.8 | 2.1 to 3.7 | <0.0001 |
Local therapy | |||
Mastectomy alone | 1.0 | ||
Mastectomy + RT | 1.1 | 0.8 to 1.5 | 0.6 |
Lumpectomy alone | 1.2 | 0.7 to 2.1 | 0.5 |
Lumpectomy + RT | 0.6 | 0.5 to 0.8 | 0.0009 |
Hormonotherapy | |||
Yes | 1.0 | ||
No | 0.7 | 0.5 to 0.9 | 0.01 |
Subtype | |||
Luminal A | 1.0 | ||
Luminal B | 1.4 | 1.1 to 1.7 | 0.02 |
Luminal HER2 | 1.4 | 0.8 to 2.2 | 0.2 |
HER2-enriched | 1.5 | 0.9 to 2.2 | 0.08 |
Basal-like | 1.2 | 0.8 to 1.8 | 0.3 |
TNP nonbasal | 1.6 | 0.9 to 2.6 | 0.06 |