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Table 7 Intrinsic subtypes’ recurrence hazard rates over time and hazard ratios (Four markers definition) a

From: Pattern of recurrence of early breast cancer is different according to intrinsic subtype and proliferation index

Years after surgery

Luminal A hazard rateb

HR

Luminal B hazard rate

HR

HER2-enriched hazard rate

HR

Triple-negative hazard rate

HR

2

0.26 (0.2 to 0.3)

1

0.50 (0.4 to 0.6)

1.9

1.26 (0.8 to 2.0)

4.8

0.78 (0.6 to 1.0)

3.0

3

0.32 (0.2 to 0.4)

1

0.54 (0.4 to 0.6)

1.7

0.63 (0.3 to 1.3)

2.0

0.60 (0.4 to 0.8)

1.9

4

0.33 (0.2 to 0.4)

1

0.43 (0.3 to 0.5)

1.3

0.28 (0.1 to 0.9)

0.8

0.39 (0.2 to 0.5)

1.2

5

0.30 (0.2 to .04)

1

0.29 (0.2 to 0.4)

1.0

0.14 (.02 to 1.0)

0.4

0.24 (0.1 to 0.4)

0.8

6

0.23 (0.1 to 0.3)

1

0.26 (0.2 to 0.5)

1.1

0.62 (0.2 to 1.7)

2.6

0.17 (.06 to 0.3)

0.7

7

0.23 (0.1 to 0.3)

1

0.31 (0.2 to 0.6)

1.4

NA

NA

0.11 (.04 to 0.3)

0.5

8

0.17 (0.1 to 0.2)

1

0.35 (0.2 to 0.7)

2.0

NA

NA

0.11 (.04 to 0.3)

0.6

9

0.15 (0.1 to 0.3)

1

0.38 (0.2 to 0.7)

2.5

NA

NA

0.10 (.03 to 0.3)

0.7

10

0.19 (0.1 to 0.4)

1

0.28 (0.1 to 0.6)

1.5

NA

NA

0.16 (.06 to 0.4)

0.8

  1. aHR, hazard ratio; HER2, human epidermal growth factor receptor 2; NA, not available. bReference value. Note: 95% confidence intervals are presented in parentheses.