Skip to main content

Table 2 Risk of death from any cause or breast cancer among adolescents and young adults (15 to 39 years of age) with breast cancer*, California, 2005 through 2009

From: Impact of breast cancer subtypes on 3-year survival among adolescent and young adult women

 

All-cause deaths

Breast cancer-specific deaths

 

Number of deaths

Model 1*

HR (95% CI)

Model 2**

HR (95% CI)

Number of deaths

Model 1*

HR (95% CI)

Model 2** †

HR (95% CI)

Subtype†

      

 HR+/HER2-

124

N/A

1.00 (reference)

100

N/A

1.00 (reference)

 HR+/HER2+

46

0.77 (0.53-1.11)

40

0.80 (0.54-1.19)

 HR-/HER2+

73

1.55 (1.10-2.18)

66

1.63 (1.12-2.36)

 Triple negative

194

2.75 (2.06-3.66)

166

2.71 (1.98-3.71)

 Unclassified

97

1.34 (0.96-1.86)

82

1.37 (0.95-1.98)

Race/ethnicity‡

      

 NH White

194

1.00 (reference)

1.00 (reference)

164

1.00 (reference)

1.00 (reference)

 NH Black

77

1.55 (1.14-2.10)

1.33 (0.98-1.82)

67

1.57 (1.12-2.20)

1.35 (0.96-1.89)

 Hispanic

199

1.08 (0.85-1.38)

1.06 (0.83-1.35)

172

1.15 (0.88-1.49)

1.12 (0.86-1.46)

 NH Asian/Pacific Islander

61

0.99 (0.73-1.35)

1.00 (0.73-1.36)

48

0.98 (0.69-1.39)

0.98 (0.69-1.39)

 Unknown

<5

N/A

N/A

<5

N/A

N/A

Marital status at diagnosis

      

 Married

284

1.00 (reference)

1.00 (reference)

241

1.00 (reference)

1.00 (reference)

 Never married

190

1.26 (1.01-1.58)

1.26 (1.01-1.57)

163

1.29 (1.01-1.64)

1.28 (1.01-1.63)

 Previously married

41

1.18 (0.81-1.70)

1.09 (0.75-1.57)

35

1.17 (0.78-1.77)

1.08 (0.72-1.63)

 Unknown

19

1.26 (0.74-2.15)

1.15 (0.67-1.95)

15

1.17 (0.64-2.15)

1.05 (0.58-1.93)

Tumor grade

      

 Low

113

1.00 (reference)

1.00 (reference)

84

1.00 (reference)

1.00 (reference)

 High

374

1.92 (1.52-2.43)

1.50 (1.17-1.93)

332

2.30 (1.76-3.01)

1.81 (1.36-2.41)

 Unknown

47

1.01 (0.60-1.71)

0.84 (0.49-1.44)

38

1.12 (0.61-2.04)

0.92 (0.50-1.70)

Lymph nodes involvement

      

 No

124

1.00 (reference)

1.00 (reference)

98

1.00 (reference)

1.00 (reference)

 Positive

372

1.15 (0.87-1.52)

1.23 (0.93-1.62)

321

1.16 (0.85-1.58)

1.24 (0.91-1.70)

 Unknown

38

0.86 (0.44-1.69)

0.84 (0.43-1.65)

35

1.11 (0.54-2.28)

1.10 (0.53-2.26)

Neighborhood SES quintile

      

 5 (highest)

73

1.00 (reference)

1.00 (reference)

60

1.00 (reference)

1.00 (reference)

 4

103

1.21 (0.87-1.68)

1.30 (0.93-1.80)

90

1.25 (0.88-1.79)

1.33 (0.93-1.90)

 3

111

1.35 (0.97-1.87)

1.41 (1.01-1.95)

92

1.27 (0.88-1.82)

1.31 (0.91-1.88)

 2

117

1.35 (0.97-1.88)

1.42 (1.02-1.98)

101

1.37 (0.96-1.96)

1.43 (1.00-2.06)

 1 (lowest)

130

1.19 (0.84-1.70)

1.23 (0.86-1.75)

111

1.13 (0.77-1.66)

1.15 (0.78-1.70)

Insurance status×

      

 Private/military insurance

272

1.00 (reference)

1.00 (reference)

222

1.00 (reference)

1.00 (reference)

 Public insurance

192

1.53 (1.21-1.92)

1.52 (1.21-1.92)

171

1.64 (1.28-2.10)

1.63 (1.27-2.10)

 No insurance

14

0.95 (0.49-1.83)

1.08 (0.56-2.09)

12

0.92 (0.44-1.92)

1.04 (0.50-2.17)

 Unknown

56

1.33 (0.94-1.88)

1.33 (0.95-1.88)

49

1.48 (1.01-2.15)

1.45 (1.00-2.11)

  1. * Cox models were adjusted for all variables in the table and age at diagnosis (continuous), tumor size (continuous), and first course of treatment (chemotherapy (y/n), radiation (y/n), and surgery (y/n)); AJCC stage levels I through IV and unknown was included as a stratifying variable.
  2. ** Cox models were additionally adjusted for subtypes of breast cancer.
  3. † Human epidermal growth factor receptor 2 (HER2), hormone receptor (HR), triple-negative (estrogen-receptor negative, progesterone-receptor negative, HER2-negative).
  4. ‡ Non-Hispanic.
  5. × Public insurance included Medicaid and other government-assisted programs; private insurance included health maintenance organizations, preferred provider organizations, managed care not otherwise specified, and military care.
Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us