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Table 4 Multivariate Cox regression analysis of survival

From: The presence and prognostic impact of apoptotic and nonapoptotic disseminated tumor cells in the bone marrow of primary breast cancer patients after neoadjuvant chemotherapy

 

DFS

OS

 

HR

Pvalue

HR

Pvalue

(95% CI)

(95% CI)

DTC status

    

   Positive versus negative

1.87 (1.09 to 3.20)

0.027

NS

 

Tumor grade

    

   Grade III versus Grade II

NS

 

3.04 (1.66 to 5.55)

<0.001

Nodal status after NACT

    

   ypN1-3 versus ypN0

2.22 (1.18 to 4.19)

0.014

NS

 

Response to NACT

    

   Nonrespondera versus

    

   responderb

2.88 (1.32 to 6.31)

0.008

2.42 (1.04 to 5.64)

0.041

  1. PFS, progression-free survival; OS overall survival; CI, confidence interval; NS, not significant; HR, hazard ratio. aStable or progressive disease; bpCR or partial response.