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Table 1 Average and standard deviation (minimum to maximum) of the mean chromophore values in tumor and normal breast tissue

From: Assessing tumor contrast in radiographically dense breast tissue using Diffuse Optical Spectroscopic Imaging (DOSI)

 

Tumor

Normal

Areola

ctO2Hb

26.8* ± 10.7

17.8 ± 4.9

20.1** ± 5.9

(9.9 to 59.1)

(9.7 to 32.9)

(10.7 to 33.2)

ctHHb

8.3* ± 2.1

5.4 ± 1.2

8.1† ± 3.0

(4.1 to 11.8)

(3.7 to 8.5)

(4.8 to 17.0)

H2O

37.9* ± 12.9

26.9 ± 10.3

45.4† ± 11.7

(17.7 to 66.5)

(17.0 to 64.3)

(25.1 to 76.6)

lipid

58.2* ± 11.3

65.9 ± 11.3

51.6† ± 10.6

(35.4 to 88.6)

(32.4 to 95.4)

(28.6 to 71.9)

TOI

6.8* ± 5.5

2.9 ± 3.4

9.5† ± 8.2

(1.3 to 25.1)

(0.9 to 18.1)

(1.8 to 38.0)

STC

1,968.9* ± 3,701.0

336.2 ± 900.2

935.1 ± 1,688.3

(21.3 to 16,509.9)

(16.1 to 4,450.0)

(21.9 to 7,085.9)

  1. *, **, † denote a statistically significant difference (Wilcoxon test at alpha = 0.05, P <0.01) between tumor and normal, between tumor and areola, and between areola and normal, respectively. ctO2Hb, Concentration of oxy-hemoglobin (μM); ctHHB, Concentration of deoxyhemoglobin (μM); STC, Specific tumor component; TOI, Tissue optical index.