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Figure 3 | Breast Cancer Research

Figure 3

From: Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers

Figure 3

Time-dependent assessment of combinations of different markers of proliferation and estrogen receptor (ER)-related genes. Landmark analyses of the Kaplan-Meier estimates of distant event-free survival (DEFS) during the first 5 years (left side of each panel) and from 5 to 10 years (right side of each panel) are shown for tamoxifen-treated patients according to four biomarker groups by combining mitosis kinase score (MKS) (low and high) and estrogen-related score (ERS) (high and low) in ER-positive/human epidermal growth factor (HER)2-negative low proliferation tumors (A) and high-proliferation tumors (B) by the three-gene model [21]; in Luminal A (C) and luminal B (D) by PAM50; and in low risk (E) and high risk (F) by Mammaprint. loP, low MKS; hiP, high MKS; loER, low ERS; hiER, high ERS.

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Breast Cancer Research

ISSN: 1465-542X

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