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Table 4 Adjusted odds ratios for Luminal B, HER2 + enriched, and triple-negative tumors compared with having a Luminal A tumor

From: Breast cancer receptor status and stage at diagnosis in over 1,200 consecutive public hospital patients in Soweto, South Africa: a case series

  Luminal B (n= 148) vs Luminal A (n= 545) HER2P enriched (n= 116) vs Luminal A (n= 545) Triple negative (n= 209) vs Luminal A (n= 545)
Odds ratio (95% CI) Odds ratio (95% CI) Odds ratio (95% CI)
Age (years) <40 1.04 (0.60, 1.79) 1.11 (0.58, 2.13) 0.94 (0.53, 1.65)
40–49 1 1 1
50–59 0.61 (0.36, 1.04) 1.08 (0.61, 1.91) 1.70 (1.09, 2.67)
60–69 0.54 (0.31, 0.96) 0.75 (0.40, 1.41) 0.78 (0.46, 1.33)
70–79 0.69 (0.38, 1.28) 0.69 (0.33, 1.46) 0.84 (0.47, 1.52)
≥80 0.30 (0.10, 0.91) 0.50 (0.16, 1.53) 0.84 (0.39, 1.81)
  P trend = 0.003 P trend = 0.21 P trend = 0.33
Calendar year 2006–2007 1 1 1
2008–2009 1.57 (0.83, 2.91) 0.93 (0.51, 1.69) 1.35 (0.76, 2.39)
2010–2012 1.00 (0.54, 1.85) 0.49 (0.27, 0.89) 1.12 (0.64, 1.94)
  P trend = 0.27 P trend = 0.003 P trend = 0.96
Stage I–II 1 1 1
III–IV 1.41 (0.98, 2.04) 2.34 (1.53, 3.59) 1.67 (1.20, 2.32)
Tumor grade 1 1 1 1
2 1.16 (0.59, 2.31) 2.54 (0.75, 8.59) 1.62 (0.73, 3.60)
3 2.35 (1.17, 4.73) 8.65 (2.59, 28.9) 7.70 (3.52, 16.8)
Missing 1.72 (0.74, 4.01) 4.61 (1.23, 17.26) 2.99 (1.21, 7.37)
Ethnicity Black 1 1 1
Nonblacka 0.95 (0.52, 1.71) 0.40 (0.17, 0.96) 0.47 (0.24, 0.89)
White 1.02 (0.42, 2.44) 0.34 (0.08, 1.49) 0.50 (0.19, 1.35)
Colored 0.70 (0.26, 1.91) 0.44 (0.13, 1.53) 0.36 (0.12, 1.07)
Asian 1.37 (0.41, 4.30) 0.41 (0.05, 3.27) 0.63 (0.17, 2.32)
  1. Note: Odds ratios are adjusted for age, stage, year, and race, unless this is the variable of interest.
  2. aNonblack women are the combined group of white, colored, and Asian women.
  3. Owing to these suggestions of racial variations in ER status, subsequent Figures 2 and 3 were restricted to black women only (that is, the more homogeneous group and population of main interest).
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