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Table 3 Risk ratio for ERN, PRN, and HER2P breast cancer

From: Breast cancer receptor status and stage at diagnosis in over 1,200 consecutive public hospital patients in Soweto, South Africa: a case series

  

Risk ratio of ERN breast cancer

Risk ratio of PRN breast cancer

Risk ratio of HER2P breast cancer

Factor

Category

Crude RR

Adjusted RR

Crude RR

Adjusted RR

Crude

Adjusted RR

   

RR

95% CI

 

RR

95% CI

 

RR

95% CI

Age (years)

<40

1.08

1.11

0.84, 1.45

1.06

1.06

0.85, 1.32

1.04

1.02

0.76, 1.38

40–49 (ref)

1

1

-

1

1

-

1

1

-

50–59

1.38

1.33

1.08, 1.65

1.39

1.37

1.16, 1.61

0.74

0.74

0.56, 0.99

60–69

0.93

0.92

0.70, 1.20

1.01

1.03

0.83, 1.26

0.75

0.75

0.54, 1.03

70–79

0.96

0.95

0.70, 1.29

0.86

0.87

0.67, 1.13

0.79

0.80

0.56, 1.15

≥80

0.91

0.89

0.57, 1.38

0.92

0.86

0.60, 1.23

0.49

0.49

0.25, 0.94

per 5 years

0.99

0.99

0.95, 1.02

0.99

0.99

0.97, 1.01

0.95

0.95

0.92, 0.99

   

P t = 0.37

  

P t = 0.27

  

p t = 0.01

Calendar year

2006–2007

1.10

1.05

0.84, 1.32

0.97

0.91

0.76, 1.08

0.97

0.94

0.69, 1.28

2008–2009 (ref)

1

1

-

1

1

-

1

1

-

2010–2012

0.86

0.84

0.71, 1.00

0.84

0.82

0.72, 0.94

0.71

0.70

0.56, 0.88

   

P = 0.03

  

P t = 0.09

  

p = 0.01

Stage

I (ref)

1

1

-

1

1

-

1

1

-

II

1.25

1.23

0.75, 2.02

1.47

1.55

1.00, 2.41

0.83

0.89

0.54, 1.44

III

1.84

1.76

1.08, 2.85

1.92

1.99

1.29, 3.09

1.15

1.22

0.76, 1.98

IV

1.52

1.48

0.85, 2.57

1.93

1.92

1.20, 3.07

1.11

1.19

0.67, 2.11

   

P t = 0.001

  

P t = 0.001

  

p t = 0.05

Tumor grade

1 (ref)

1

1

-

1

1

 

1

1

-

2

2.09

1.94

1.11, 3.37

1.48

1.42

0.99, 2.04

1.48

1.30

0.79, 2.15

3

4.40

3.95

2.30, 6.79

2.52

2.37

1.67, 3.36

2.12

1.80

1.10, 2.95

Missing

3.14

2.83

1.58, 5.04

2.18

1.96

1.34, 2.86

1.82

1.63

0.93, 2.86

         

p = 0.01

Ethnicity

Black (ref)

1

1

-

1

1

-

1

1

-

Nonblacka

0.61

0.61

0.42, 0.89

0.71

0.73

0.55, 0.95

0.89

0.86

0.59, 1.25

   

P = 0.009

  

P = 0.02

  

p = 0.42

White

0.55

0.55

0.29, 1.01

0.67

0.69

0.44, 1.07

0.91

0.87

0.49, 1.55

Colored

0.63

0.63

0.35, 1.11

0.69

0.70

0.45, 1.09

0.81

0.77

0.41, 1.43

Asian

0.68

0.72

0.34,1.53

0.83

0.81

0.48, 1.38

1.01

0.99

0.47, 2.09

   

P = 0.08

  

P = 0.13

  

p = 0.86

  1. Note: Analyses based on 1,063 women for ER, 1,058 for PR, and 1,021 for HER2. Adjusted RRs are adjusted for age, stage, year, and race, unless this is the variable of interest. P values denote test of heterogeneity across categories; Pt denotes test of linear trend.
  2. aNonblack women are the combined group of white, colored, and Asian women.
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Breast Cancer Research

ISSN: 1465-542X

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