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Table 2 Distribution of ER, PR, HER2, and their combinations by woman and tumor characteristics

From: Breast cancer receptor status and stage at diagnosis in over 1,200 consecutive public hospital patients in Soweto, South Africa: a case series

  ER status PR status HER2 status ER, PR, and HER2 status number of women ER, PR, and HER2 status row distribution (%)
Number positive Number negative % ER negative Number positive Number negative % PR negative Number positive Number negative % HER2 positive Luminal A Luminal B HER2P-enriched TRN Luminal A Luminal B HER2P-enriched TRN
All women 688 375 35.3† 559 499 47.2† 756 265 26.0† 545 149 116 209 53.5 14.6 11.4 20.5
Age <40 100 54 35.1 84 71 45.8 102 48 32.0 77 29 19 25 51.3 19.3 12.7 16.7
40–49 177 85 32.4 148 113 43.3 173 77 30.8 128 47 30 45 51.2 18.8 12.0 18.0
50–59 149 121 44.8 107 162 60.2 199 59 22.9 123 28 31 75 47.9 10.9 12.1 29.2
60–69 134 58 30.2 106 83 43.9 141 42 23.0 109 22 20 31 59.9 12.1 11.0 17.0
70–79 90 41 31.3 82 49 37.4 96 31 24.4 74 19 12 22 58.3 15.0 9.5 17.3
≥80 38 16 29.6 32 21 39.6 45 8 15.1 34 4 4 11 64.2 7.6 7.6 20.8
Calendar year 2006–2007 86 60 41.1 72 72 50.0 87 37 29.8 66 16 21 21 53.2 12.9 16.9 16.9
2008–2009 241 144 37.4 186 198 51.6 263 116 30.6 183 65 51 80 48.3 17.2 13.5 21.1
2010–2012 361 171 32.1 301 229 43.2 406 112 21.6 296 68 44 108 57.4 13.2 8.5 20.9
Stage I 43 13 23.2 41 16 28.1 40 14 25.9 34 10 4 6 63.0 18.5 7.4 11.1
II 319 130 29.0 262 184 41.3 345 95 21.6 262 60 35 81 59.8 13.7 8.0 18.5
III 271 202 42.7 218 254 53.8 314 133 29.8 207 68 65 107 46.3 15.2 14.5 23.9
IV 55 30 35.3 38 45 54.2 57 23 28.8 42 11 12 15 52.5 13.8 15.0 18.8
Tumor grade 1 89 12 11.9 76 25 24.8 84 15 15.2 76 12 3 8 76.7 12.1 3.0 8.1
2 331 109 24.8 278 161 36.7 332 96 22.4 276 60 36 55 64.6 14.1 8.4 12.9
3 189 207 52.3 148 246 62.4 264 125 32.1 138 61 64 125 35.6 15.7 16.5 32.2
Missing 79 47 37.3 57 67 54.0 76 29 27.6 55 16 13 21 52.4 15.2 12.4 20.0
Ethnicity Black 606 351 36.7 492 461 48.4 679 240 23.1 481 131 109 196 52.5 14.3 11.9 20.4
White 32 8 20.0 27 13 32.5 29 9 23.7 24 7 2 5 63.2 18.4 5.3 13.2
Colored 30 9 23.1 26 13 33.3 30 8 21.1 26 5 3 4 68.4 13.2 7.9 10.5
Asian 15 5 36.7 12 8 40.0 14 5 25.3 11 4 1 3 57.9 21.1 6.3 15.8
  1. Note: Percentages are among women with known receptor status. Numbers missing are provided in Table 1.
  2. †Percentages (95% confidences intervals) are 35.3 (32.4 to 38.2) for ERN, 47.2 (44.2 to 50.2) for PRN, and 26.0 (23.3 to 28.6) for HER2P.
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