Table 1 Characteristics of incident breast cancers diagnosed during October 2006 through July 2012 at Chris Hani Baragwanath Academic Hospital Breast Clinic, Soweto, South Africa
Characteristic | Variable completeness (%) | Category | No. (column % among nonmissing data) |
|---|---|---|---|
Among all incident breast cancers (N = 1247) | |||
Sex | 100 | Male | 12 (1.0) |
Female | 1232 (99.0) | ||
Invasiveness in women | 100 | Non-invasive | 19 (1.5) |
Invasive | 1216 (98.5) | ||
Among invasive incident breast cancers in women (N = 1216) | |||
Ethnicity | 99.4 | Black | 1,092 (90.3) |
White | 49 (4.1) | ||
Colored | 46 (3.8) | ||
Asian | 22 (1.8) | ||
Age at diagnosis (years) | <40 | 182 (15.0) | |
40–49 | 290 (23.9) | ||
50–59 | 310 (25.5) | ||
60–69 | 221 (18.2) | ||
70–79 | 147 (12.1) | ||
≥80 | 66 (5.4) | ||
Year of diagnosis | 100 | 2006–2007 | 172 (14.1) |
2008–2009 | 431 (35.4) | ||
2010–2012 | 613 (50.4) | ||
HIV status | 69.0 | Negative | 686 (81.8) |
Positive | 153 (18.2) | ||
Stage | 98.1 | I | 61 (5.1) |
IIA | 211 (17.7) | ||
IIB | 280 (23.5) | ||
IIIA | 148 (12.4) | ||
IIIB-IIIC | 385 (32.3) | ||
IV metastases | 107 (9.0) | ||
Tumor grade | 80.0 | 1 = Well-differentiated | 106 (10.9) |
2 = Moderately-differentiated | 455 (46.8) | ||
3 = Poorly-differentiated | 412 (42.3) | ||
ER | 88.2 | Negative | 376 (35.1) |
Positive: of which | 696 (64.9) | ||
Positive stain score +1 | 96 | ||
+2 | 155 | ||
+3 | 445 | ||
PR | 87.8 | Negative | 500 (46.9) |
Positive, of which: | 567 (53.1) | ||
Positive staining score +1 | 111 | ||
+2 | 163 | ||
+3 | 293 | ||
HER2 | 84.9 | Negative, of which: | 762 (74.1) |
Negative stain score 0 | 404 | ||
+1 | 142 | ||
+2 | 216 | ||
Positive (+3) | 267 (26.0) | ||
Subtypes abbreviations: | 84.5 | Luminal A (ERP and/or PRP, HER2N) | 551 (53.7) |
Luminal B (ERP and/or PRP, HER2P) | 150 (14.6) | ||
HER2P enriched (ERN, PRN, HER2P) | 117 (11.04) | ||
Triple negative (ERN, PRN, HER2N) | 209 (20.4) | ||