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Figure 5 | Breast Cancer Research

Figure 5

From: Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition

Figure 5

Parthenolide and costunolide reduce reattachment efficiency of human breast carcinoma cells. Real-time electrical impedance monitoring shows that parthenolide (10 μM) and costunolide (25 μM) significantly reduce attachment when compared to vehicle while Taxol (0.5 μg/ml) and resveratrol (50 μg/ml) did not. Colchicine (50 μM) reduced attachment to a greater extent in Bt-549 than in MDA-MB-157. Lines, mean for three triplicate wells; bars, SD; representative graph is shown. Three independent experiments were performed [see Additional file 4: Figure S4].

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Breast Cancer Research

ISSN: 1465-542X

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