Figure 1
From: MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer
MicroRNA 510 promotes migration, invasion and colony formation in vitro. Transwell migration (A), matrigel invasion (B) and colony formation (C) assays of 3 independent stable clones over-expressing miR-510 (510-1, 510-10 and 510-11) compared to vector control (pSupp-4). Quantitation of haptokinetic migration (Pacman) assay of MCF10A (D) and MCF7 (E) cells stably infected with miR-510 (510) compared to stable infected scrambled control (scr). (F) Transwell migration assay of MDA MB 231 cells stably infected with miR-510 (510) compared to stable infected scrambled control (scr). (G) Transwell migration assay of CAMA-1 cells transfected with antisense oligonucleoteide against miR-510 (ASO-510) or scrambled control (scr). (H) Transwell migration assay of BT549 cells transfected with increasing concentrations of anti-miR-510 vector (anti-510) or scrambled vector control (scr). *P < 0.05.