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Table 2 Correlation of PIK3CA mutation status with clinicopathological parameters

From: PIK3CA mutations are frequently observed in BRCAX but not BRCA2-associated male breast cancer

  PIK3CAMutation (n = 6) PIK3CAWild type (n = 51) P-value
Age - mean (years) 62.2 63.0 0.899
Overall DSS 33.3% 33.3% 1.000
Carrier mutation status    
BRCA1 1 2 0.288
BRCA2 0 25 0.030
BRCAX 5 24 0.194
Primary tumour size (mm) 18.8 19.1 0.948
Histological type    
Invasive carcinoma - no special type (IC - NST) 6 37 0.319
IC-NST with micropapillary areas 0 9 0.575
Invasive Papillary Carcinoma 0 3 1.000
Invasive Lobular Carcinoma 0 2 1.000
Tumour grade    
1 0 3 1.000
2 3 26 1.000
3 3 22 1.000
Lymphovascular invasion 33.3% 39.2% 1.000
Perineural invasion 50.0% 41.2% 0.689
Intrinsic subtype    
Luminal 6 45 1.000
HER2 0 5 1.000
Basal 0 1 1.000
Null 0 0 1.000
  1. P-values < 0.05 in bold text.