Figure 3From: Progestin effects on cell proliferation pathways in the postmenopausal mammary glandHormone therapy effects on gene markers related to ER expression and activation. (a) Hormone therapy effects on gene markers related to oestrogen receptor (ER) activation; (b) ER expression; (c) estradiol synthesis and bioactivation; and (d) estradiol deactivation. mRNA expression levels were determined by quantitative PCR. Vertical lines indicate 90% confidence interval. Letters indicate significant differences compared with control (P < 0.05a, P < 0.01b, P < 0.001c) and conjugated equine estrogens plus medroxyprogesterone acetate (CEE + MPA) (P < 0.01d, P < 0.001e) groups.Back to article page