Figure 2

Diagnostic distributions of spectral parameters and immunohistochemistry correlates. (a-e) Boxplots of recovered spectral parameters for all tissues per pathology subtype, indicated by color: normal (including fibrocystic disease) (green), fibroadenoma (blue), ductal carcinoma in situ (pink), invasive cancer (red), and partially treated invasive cancer after neoadjuvant chemotherapy (orange). (f) Corresponding boxplots of immunohistochemical measures of percentage of stroma, epithelium, and fat, and CD31-positive, CD105-positive mean vascular density (MVD) and area (MVA). Box plot red bars indicate the population median; green dots indicate the mean value per patient ROI; and red crosses indicate outliers.