Table 1 Patient characteristics

Number of patients

20

5

Average age (years)

59.7 (6.28)

59.5 (4.76)

Average BMI (kg/m²)

36.6 (5.04)**

21.1 (2.17)

Average serum concentrations

   Free IGF-1 (ng/ml)

4.92 (0.925)

5.43 (1.80)

   Insulin (pg/ml)

742.9 (156.8)

157.4 (44.1)

   Interleukin 6 (pg/ml)

4.6 (0.58)*

1.6 (0.29)

   TNF-α (pg/ml)

7.1 (0.51)*

4.6 (0.19)

   Leptin (ng/ml)

36.6 (4.67)**

6.40 (3.86)

   Adiponectin (ug/ml)

54.5 (6.55)*

97.5 (32.0)

Ethnicity/race

   Hispanic

12

0

   White

6

3

   African-American

2

0

   Asian

0

1

   Not Available

0

1

Confounding conditions

   Diabetes

5

0

   Hypercholesterolemia

8

0

   Hypertension

14

1

Medications

   Aromatase inhibitor

9

1

   Tamoxifen

5

2

   Chemotherapy

6

2

   Metformin

5

0

   Statin

8

0