Table 2 Mean absolute change of percent density (PD) from baseline until first follow-up mammogram
N | Meandecrease (%-units) | 95% CI for mean decrease of PD | P-value | |
|---|---|---|---|---|
Total | 422 | -3.94 | -4.89, -3.00 | - |
CBC case/control status | 0.09 | |||
Cases | 211 | -3.13 | -4.39, -1.87 | |
Controls | 211 | -4.75 | -6.16, -3.34 | |
Age at time of (first) cancer: | <0.01 | |||
<45 years | 74 | -5.30 | -8.39, -2.22 | |
45 to 54 years | 136 | -5.85 | -7.61, -4.10 | |
55 to 64 years | 112 | -4.13 | -5.60, -2.65 | |
≥65 years | 100 | -0.13 | -1.50, 1.25 | |
Calendar period of (first) cancer: | 0.25 | |||
1976 to 1980 | 62 | -4.11 | -7.57, -0.66 | |
1981 to 1985 | 80 | -3.78 | -6.24, -0.32 | |
1986 to 1990 | 90 | -2.27 | -4.09, -0.46 | |
1991 to 1995 | 102 | -3.91 | -5.70, -2.12 | |
1996 to 2005 | 88 | -5.71 | -7.26, -4.16 | |
Total breast area at baseline: | 0.27 | |||
Smallest quartile | 103 | -2.54 | -4.66, -0.41 | |
2 nd quartile | 105 | -4.68 | -6.71, -2.66 | |
3 rd quartile | 110 | -4.91 | -6.75, -3.07 | |
Largest quartile | 104 | -3.56 | -5.16, -1.96 | |
Adjuvant therapy of (first) cancer: | <0.01 | |||
No adjuvant therapy | 78 | -1.09 | -3.09, 0.92 | |
Radiotherapy only | 114 | -3.22 | -5.14, -1.30 | |
Endocrine therapy (with/without radiotherapy) | 174 | -4.15 | -5.37, -2.93 | |
Chemotherapy (with/without other adjuvant therapy) | 56 | -8.74 | -5.24, -12.24 | |
Menopause status at (first) cancer:* | <0.01 | |||
Premenopausal | 173 | -5.90 | -7.70, -4.10 | |
Postmenopausal | 243 | -2.56 | -3.54, -1.58 | |
Postmenopausal HRT use:* | <0.01 | |||
with Current use of HRT at diagnosis | 51 | -6.55 | -8.90, -4.19 | |
with No current use of HRT at diagnosis | 127 | -1.66 | -2.90, -0.43 | |
ER-status of (first) cancer: | 0.63 | |||
ER-positive | 295 | -4.15 | -5.29, -3.01 | |
ER-negative | 53 | -3.46 | -5.92, -0.99 | |
TNM-stage of (first) cancer:* | 0.67 | |||
1 | 244 | -4.06 | -5.27, -2.85 | |
2 | 157 | -3.48 | -5.10, -1.86 | |
3 | 16 | -5.36 | -11.19, 0.47 |