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Table 4 Association between mammographic density categorized into quartiles and local and locoregional recurrence

From: Possible influence of mammographic density on local and locoregional recurrence of breast cancer

 

Local recurrence

Locoregional recurrence

 

HR

95% CI

Pvalue

HR

95% CI

Pvalue

Model 1a

  

0.008

  

0.012

PD, 1st quartileb

1.00 (Ref.)

  

1.00 (Ref.)

  

PD, 2nd quartilec

1.72

0.78-3.78

 

1.43

0.79-2.60

 

PD, 3rd quartiled

1.91

0.86-4.24

 

1.34

0.72-2.50

 

PD, 4th quartilee

3.14

1.38-7.16

 

2.36

1.27-4.39

 

Model 2f

  

0.017

  

0.035

PD, 1st quartileb

1.00 (Ref.)

  

1.00 (Ref.)

  

PD, 2nd quartilec

1.80

0.80-4.05

 

1.38

0.75-2.53

 

PD, 3rd quartiled

1.78

0.77-4.11

 

1.29

0.68-2.45

 

PD, 4th quartilee

3.03

1.28-7.17

 

2.10

1.11-3.97

 
  1. aAdjusted for age, body mass index (BMI), and hormone replacement therapy (HRT) use;
  2. bpercentage density (PD) <6.46, n = 443;
  3. c6.46 ≤ PD <13.66, n = 444;
  4. dPD 13.66 ≤ PD <25.07, n = 444;
  5. ePD ≥25.07, n = 443;
  6. fadjusted for age, BMI, HRT use, mode of detection, tumor size, lymph node metastasis, estrogen receptor status, progesterone receptor status, and grade. CI, confidence interval; HR, hazard ratio; Ref., reference value.
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Breast Cancer Research

ISSN: 1465-542X

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