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Figure 1 | Breast Cancer Research

Figure 1

From: BreastMark: An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome

Figure 1

Prognostic role of the Ki67, Survivn MYBL2 and MMP11 in breast cancer. These figures were generated using BreastMark at http://glados.ucd.ie/BreastMark/index.html. (a) Kaplan-Meier estimates of survival, demonstrating high expression of Ki67 is associated with poor prognosis in breast cancer (n = 902, HR = 1.68, P = 4.44e-05). (b) Kaplan-Meier estimate of survival, demonstrating that high expression of Ki67 and Survivin in combination have a greater effect on survival (n = 902, HR = 1.99, P = 5.60e-08). (c) Kaplan-Meier estimate of survival, demonstrating that high expression of Ki67, Survivin and MYBL2 in combination have an even greater effect on survival (n = 902, HR = 2.00, P = 2.01e-07). (d) Kaplan-Meier estimate of survival, demonstrating how the invasion marker MMP11 does not improve the prognostic ability of Ki67 and Survivin (n = 902, HR = 1.54, P = 9.20e-03). HR, hazard ratio.

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Breast Cancer Research

ISSN: 1465-542X

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