Skip to main content
Figure 3 | Breast Cancer Research

Figure 3

From: Elevated expression of syntenin in breast cancer is correlated with lymph node metastasis and poor patient survival

Figure 3

Syntenin overexpression promotes breast tumor growth and lung metastasis in vivo. (A) Overexpression of syntenin promoted breast tumor growth in nude mice (P < 0.01). (B) Volumes of tumors formed by syntenin-knockdown cells were significantly smaller than control. Bars, SEM. Five mice in each group were used in this study. (C, D) Hematoxylin-eosin (HE) was used to examine the number of lung metastasis (200×). Quantification of average metastasis number of per lung (n = 5). (E, F) Immunohistochemistry examination of CD31 for microvessels in the final week of xenografts (200×). Quantification of average microvessel density per xenografts (n = 5). *P < 0.05.

Back to article page