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Table 2 Multivariate regression of baseline characteristics and the first principal component with adjusted percent mammographic density

From: High mammographic density in women of Ashkenazi Jewish descent

 

Univariate analyses

Multivariate analysis

 

Odds ratio (95% confidence interval)

Pvalue

Odds ratio (95% confidence interval)

Pvalue

First principal component

2.00 (1.26 to 3.17)

0.003

2.22 (1.36 to 3.65)

0.002

Body mass index

    

   First quartile (<21 kg/m2)

Reference

 

Reference

 

   Second quartile (21 to 23 kg/m2)

0.41 (0.28 to 0.59)

<0.001

0.38 (0.26 to 0.57)

<0.001

   Third quartile (23 to 26 kg/m2)

0.33 (0.23 to 0.49)

<0.001

0.31 (0.21 to 0.46)

<0.001

   Fourth quartile (>26 kg/m2)

0.44 (0.30 to 0.63)

<0.001

0.48 (0.32 to 0.71)

<0.001

Age at first live birth

    

   <30 years

Reference

 

Reference

 

   ≥30 years or nulliparous

1.27 (0.93 to 1.72)

0.1

1.13 (0.80 to 1.59)

0.5

Menopausal status

    

   Premenopausal

Reference

 

Reference

 

   Postmenopausal

0.67 (0.50 to 0.90)

0.009

0.67 (0.49 to 0.92)

0.01

   Postmenopausal on hormone therapy

0.72 (0.49 to 1.06)

0.1

0.74 (0.49 to 1.10)

0.1

  1. Odds ratios are for likelihood of having high adjusted percent mammographic density compared with low adjusted percent mammographic density. Univariate and multivariate P values are calculated using chi-squared tests.