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Table 1 Characteristics of women with high adjusted percent mammographic density versus low adjusted percent mammographic density

From: High mammographic density in women of Ashkenazi Jewish descent

  High adjusted PMD Low adjusted PMD P value
Percent dense tissue by volume 72.7 (13.3) 29.6 (6.4) <10-3
Volume of dense breast tissue (ml) 327.3 (215.0) 166.2 (70.2) <10-3
Volume of the breast (ml) 479.1 (354.6) 576.5 (242.9) <10-3
Age (years) 52.4 (9.7) 51.7 (7.8) 0.9
Body mass index (kg/m2) 24.1 (6.5) 23.9 (3.1) <10-3
Age at first live birth    0.1
   <30 years 96 (20%) 114 (24%)  
   ≥30 years or nulliparous 378 (80%) 354 (76%)  
   Unknown 0 1  
Menopausal status    
   Premenopausal 203 (43.3%) 159 (34.3%)  
   Postmenopausal 157 (33.5%) 183 (39.4%) 0.009*
   Postmenopausal on hormone therapy 71 (15.1%) 77 (16.6%) 0.7**
   Unknown 38 (8.1%) 45 (9.7%)  
First-degree relative with breast cancer    0.02
   Yes 114 (24%) 84 (18%)  
   No 366 (76%) 383 (82%)  
   Unknown 0 2  
  1. Data presented as mean (standard deviation) or n (%). PMD, percent mammographic density. Chi-squared P values calculated excluding the samples with unknown values. *P value for comparison with premenopausal women. **P value for comparison with postmenopausal women not taking hormone therapy.