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Table 1 Characteristics of women with high adjusted percent mammographic density versus low adjusted percent mammographic density

From: High mammographic density in women of Ashkenazi Jewish descent

 

High adjusted PMD

Low adjusted PMD

P value

Percent dense tissue by volume

72.7 (13.3)

29.6 (6.4)

<10-3

Volume of dense breast tissue (ml)

327.3 (215.0)

166.2 (70.2)

<10-3

Volume of the breast (ml)

479.1 (354.6)

576.5 (242.9)

<10-3

Age (years)

52.4 (9.7)

51.7 (7.8)

0.9

Body mass index (kg/m2)

24.1 (6.5)

23.9 (3.1)

<10-3

Age at first live birth

  

0.1

   <30 years

96 (20%)

114 (24%)

 

   ≥30 years or nulliparous

378 (80%)

354 (76%)

 

   Unknown

0

1

 

Menopausal status

   

   Premenopausal

203 (43.3%)

159 (34.3%)

 

   Postmenopausal

157 (33.5%)

183 (39.4%)

0.009*

   Postmenopausal on hormone therapy

71 (15.1%)

77 (16.6%)

0.7**

   Unknown

38 (8.1%)

45 (9.7%)

 

First-degree relative with breast cancer

  

0.02

   Yes

114 (24%)

84 (18%)

 

   No

366 (76%)

383 (82%)

 

   Unknown

0

2

 
  1. Data presented as mean (standard deviation) or n (%). PMD, percent mammographic density. Chi-squared P values calculated excluding the samples with unknown values. *P value for comparison with premenopausal women. **P value for comparison with postmenopausal women not taking hormone therapy.