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Figure 2 | Breast Cancer Research

Figure 2

From: Progesterone metabolites regulate induction, growth, and suppression of estrogen- and progesterone receptor-negative human breast cell tumors

Figure 2

Opposing in vitro effects of 5αP and 3αHP on proliferation of MDA-MB-231 cells used in the in vivo (xenograft) studies. Cells were seeded at 4 × 104 cells per dish, allowed to attach for 24 hours, and then treated for 72 hours without (C, control) or with 10-6 M 5αP and/or 3αHP, and proliferation was determined by cell counts. Data are presented as cell number (mean and SEM; n = 4). **P < 0.01, ***P < 0.001 for the indicated comparisons or versus the control.

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