TY - BOOK PY - 2011 DA - 2011// TI - Global Cancer Facts & Figures PB - Atlanta CY - American Cancer Society ID - ref1 ER - TY - JOUR AU - Key, T. J. AU - Pike, M. C. PY - 1988 DA - 1988// TI - The role of estrogens and progestogens in the epidemiology and prevention of breast cancer JO - Eur J Cancer Clin Oncol VL - 24 UR - https://doi.org/10.1016/0277-5379(88)90173-3 DO - 10.1016/0277-5379(88)90173-3 ID - Key1988 ER - TY - JOUR AU - Henderson, B. E. AU - Feigelson, H. S. PY - 2000 DA - 2000// TI - Hormonal carcinogenesis JO - Carcinogenesis VL - 21 UR - https://doi.org/10.1093/carcin/21.3.427 DO - 10.1093/carcin/21.3.427 ID - Henderson2000 ER - TY - JOUR AU - McGuire, W. L. AU - Osborne, C. K. AU - Clark, G. M. AU - Knight, W. A. PY - 1982 DA - 1982// TI - Steroid hormone receptors and carcinoma of the breast JO - Am J Physiol VL - 243 ID - McGuire1982 ER - TY - JOUR AU - Aaltomaa, S. AU - Lipponen, P. AU - Eskelinen, M. AU - Kosma, V. M. AU - Marin, S. AU - Alhava, E. AU - Syrjanen, K. PY - 1991 DA - 1991// TI - Hormone receptors as prognostic factors in female breast cancer JO - Ann Med VL - 6 UR - https://doi.org/10.3109/07853899109148097 DO - 10.3109/07853899109148097 ID - Aaltomaa1991 ER - TY - JOUR AU - Howat, J. M. T. AU - Harris, M. AU - Swindell, R. AU - Barnes, D. M. PY - 1985 DA - 1985// TI - The effect of oestrogen and progesterone receptors on recurrence and survival in patients with carcinoma of the breast JO - Br J Cancer VL - 51 UR - https://doi.org/10.1038/bjc.1985.38 DO - 10.1038/bjc.1985.38 ID - Howat1985 ER - TY - JOUR AU - Taucher, S. AU - Rudas, M. AU - Gnant, M. AU - Thomanek, K. AU - Dubsky, P. AU - Roka, S. AU - Bachleitner, T. AU - Kandioler, D. AU - Wenzel, C. AU - Steger, G. AU - Mittlböck, M. AU - Jakesz, R. PY - 2003 DA - 2003// TI - Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy JO - Endocr Relat Cancer VL - 10 UR - https://doi.org/10.1677/erc.0.0100091 DO - 10.1677/erc.0.0100091 ID - Taucher2003 ER - TY - JOUR AU - Rexhepaj, E. AU - Brennan, D. J. AU - Holloway, P. AU - Kay, E. W. AU - McCann, A. H. AU - Landberg, G. AU - Duffy, M. J. AU - Jirstrom, K. AU - Gallagher, W. M. PY - 2008 DA - 2008// TI - Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer JO - Breast Cancer Res VL - 10 UR - https://doi.org/10.1186/bcr2187 DO - 10.1186/bcr2187 ID - Rexhepaj2008 ER - TY - JOUR AU - Robinson, G. W. AU - Hennighausen, L. AU - Johnson, P. F. PY - 2000 DA - 2000// TI - Side-branching in the mammary gland: the progesterone-Wnt connection JO - Genes Dev VL - 14 ID - Robinson2000 ER - TY - JOUR AU - Paone, J. F. AU - Abeloff, M. D. AU - Ettinger, D. S. AU - Arnold, E. A. AU - Baker, P. R. PY - 1981 DA - 1981// TI - The correlation of estrogen and progesterone receptor levels with response to chemotherapy for advanced carcinoma of the breast JO - Surg Gynecol Obstet VL - 152 ID - Paone1981 ER - TY - JOUR AU - Vollenweider-Zerargui, L. AU - Barrelet, L. AU - Wong, Y. AU - Lemarchand-Béraud, T. AU - Gómez, F. PY - 1986 DA - 1986// TI - The predictive value of estrogen and progesterone receptors' concentrations on the clinical behavior of breast cancer in women: clinical correlation on 547 patients JO - Cancer VL - 57 UR - https://doi.org/3.0.CO;2-X DO - 3.0.CO;2-X ID - Vollenweider-Zerargui1986 ER - TY - JOUR AU - Fisher, B. AU - Redmond, C. AU - Fisher, E. R. AU - Caplan, R. PY - 1988 DA - 1988// TI - Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: findings from National Surgical Adjuvant Breast and Bowel Project Protocol B-06 JO - J Clin Oncol VL - 7 ID - Fisher1988 ER - TY - JOUR AU - Bardou, V. -. J. AU - Arpino, G. AU - Elledge, R. M. AU - Osborne, C. K. AU - Clark, G. M. PY - 2003 DA - 2003// TI - Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer data bases JO - J Clin Oncol VL - 21 UR - https://doi.org/10.1200/JCO.2003.09.099 DO - 10.1200/JCO.2003.09.099 ID - Bardou2003 ER - TY - JOUR AU - Dunnwald, L. K. AU - Rossing, M. A. AU - Li, C. I. PY - 2007 DA - 2007// TI - Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients JO - Breast Cancer Res VL - 9 UR - https://doi.org/10.1186/bcr1639 DO - 10.1186/bcr1639 ID - Dunnwald2007 ER - TY - JOUR AU - Wiebe, J. P. AU - Muzia, D. AU - Hu, J. AU - Szwajcer, D. AU - Hill, S. A. AU - Seachrist, J. L. PY - 2000 DA - 2000// TI - The 4-pregnene and 5α-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion JO - Cancer Res VL - 60 ID - Wiebe2000 ER - TY - JOUR AU - Wiebe, J. P. AU - Lewis, M. J. PY - 2003 DA - 2003// TI - Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydroxysteroid oxidoreductase and 3α(β)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells JO - BMC Cancer VL - 3 UR - https://doi.org/10.1186/1471-2407-3-9 DO - 10.1186/1471-2407-3-9 ID - Wiebe2003 ER - TY - JOUR AU - Wiebe, J. P. PY - 2006 DA - 2006// TI - Progesterone metabolites in breast cancer JO - Endocr Relat Cancer VL - 13 UR - https://doi.org/10.1677/erc.1.01010 DO - 10.1677/erc.1.01010 ID - Wiebe2006 ER - TY - JOUR AU - Wiebe, J. P. AU - Beausoleil, M. AU - Zhang, G. AU - Cialacu, V. PY - 2010 DA - 2010// TI - Opposing actions of the progesterone metabolites, 5α-dihydroprogesterone (5αP) and 3α-dihydroprogesterone (3αHP) on mitosis, apoptosis, and expression of BCL-2, Bax and p21 in human breast cell lines JO - J Steroid Biochem Mol Biol VL - 118 UR - https://doi.org/10.1016/j.jsbmb.2009.11.005 DO - 10.1016/j.jsbmb.2009.11.005 ID - Wiebe2010 ER - TY - JOUR AU - Weiler, P. J. AU - Wiebe, J. P. PY - 2000 DA - 2000// TI - Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5α-pregnane-3,20-dione and 3α-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells JO - Biochem Biophys Res Commun VL - 272 UR - https://doi.org/10.1006/bbrc.2000.2847 DO - 10.1006/bbrc.2000.2847 ID - Weiler2000 ER - TY - JOUR AU - Wiebe, J. P. AU - Barr, K. J. AU - Buckingham, K. D. PY - 1991 DA - 1991// TI - A radioimmunoassay for the regulatory allylic steroid, 3α-hydroxy-4-pregnen-20-one (3αHP) JO - J Steroid Biochem Mol Biol VL - 38 UR - https://doi.org/10.1016/0960-0760(91)90339-7 DO - 10.1016/0960-0760(91)90339-7 ID - Wiebe1991 ER - TY - JOUR AU - Erlanger, B. F. AU - Borek, F. AU - Beiser, S. M. AU - Lieberman, S. PY - 1957 DA - 1957// TI - Steroid-protein conjugates: preparation and characterization of conjugates of bovine serum albumin with testosterone and with cortisone JO - J Biol Chem VL - 228 ID - Erlanger1957 ER - TY - JOUR AU - Naar, J. AU - Branaa, P. AU - Chinain, M. AU - Pauillac, S. PY - 1999 DA - 1999// TI - An improved method for the microscale preparation and characterization of hapten-protein conjugates: the use of cholesterol as a model for nonchromophore hydroxylated haptens JO - Bioconjugate Chem VL - 10 UR - https://doi.org/10.1021/bc990042g DO - 10.1021/bc990042g ID - Naar1999 ER - TY - JOUR AU - Wiebe, J. P. AU - Deline, C. AU - Buckingham, K. D. AU - Dave, V. AU - Stothers, J. B. PY - 1985 DA - 1985// TI - Synthesis of the allylic gonadal steroids, 3α-hydroxy-4-pregnen-20-one and 3α-hydroxy-4-androsten-17-one, and of 3α-hydroxy-5α-pregnan-20-one JO - Steroids VL - 45 UR - https://doi.org/10.1016/0039-128X(85)90064-9 DO - 10.1016/0039-128X(85)90064-9 ID - Wiebe1985 ER - TY - JOUR AU - Price, J. E. AU - Polyzos, A. AU - Zhang, R. D. AU - Daniels, L. M. PY - 1990 DA - 1990// TI - Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice JO - Cancer Res VL - 50 ID - Price1990 ER - TY - JOUR AU - Osborne, C. K. AU - Yochmowitz, M. G. AU - Knight, W. A. AU - McGuire, W. L. PY - 1980 DA - 1980// TI - The value of estrogen and progesterone receptors in the treatment of breast cancer JO - Cancer VL - 46 UR - https://doi.org/3.0.CO;2-U DO - 3.0.CO;2-U ID - Osborne1980 ER - TY - JOUR AU - Ciocca, D. R. AU - Elledge, R. PY - 2000 DA - 2000// TI - Molecular markers for predicting response to tamoxifen in breast cancer patients JO - Endocrine VL - 13 UR - https://doi.org/10.1385/ENDO:13:1:1 DO - 10.1385/ENDO:13:1:1 ID - Ciocca2000 ER - TY - JOUR AU - Jiang, S. -. Y. AU - Jordan, V. C. PY - 1992 DA - 1992// TI - Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor JO - J Natl Cancer Inst VL - 84 UR - https://doi.org/10.1093/jnci/84.8.580 DO - 10.1093/jnci/84.8.580 ID - Jiang1992 ER - TY - JOUR AU - Lin, V. C. L. AU - Eng, A. S. AU - Hen, N. E. AU - Ng, E. H. L. AU - Chowdhury, S. H. PY - 2001 DA - 2001// TI - Effect of progesterone on the invasive properties and tumor growth of progesterone receptor-transfected breast cancer cells MDA-MB-231 JO - Clin Cancer Res VL - 7 ID - Lin2001 ER - TY - JOUR AU - Pawlak, K. J. AU - Zhang, G. AU - Wiebe, J. P. PY - 2005 DA - 2005// TI - Membrane 5α-pregnane-3,20-dione (5αP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5αP and down-regulated by the progesterone metabolites, 3α-dihydroprogesterone and 20α-dihydroprogesterone, with associated changes in cell proliferation and detachment JO - J Steroid Biochem Mol Biol VL - 97 UR - https://doi.org/10.1016/j.jsbmb.2005.05.014 DO - 10.1016/j.jsbmb.2005.05.014 ID - Pawlak2005 ER - TY - JOUR AU - Wiebe, J. P. AU - Lewis, M. J. AU - Cialacu, V. AU - Pawlak, K. J. AU - Zhang, G. PY - 2005 DA - 2005// TI - The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics JO - J Steroid Biochem Mol Biol VL - 93 UR - https://doi.org/10.1016/j.jsbmb.2004.12.003 DO - 10.1016/j.jsbmb.2004.12.003 ID - Wiebe2005 ER - TY - JOUR AU - Wiebe, J. P. AU - Muzia, D. PY - 2001 DA - 2001// TI - The endogenous progesterone metabolite, 5α-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells JO - Endocrine VL - 16 UR - https://doi.org/10.1385/ENDO:16:1:07 DO - 10.1385/ENDO:16:1:07 ID - Wiebe2001 ER - TY - JOUR AU - Beck, C. A. AU - Wolfe, M. AU - Murphy, L. D. AU - Wiebe, J. P. PY - 1997 DA - 1997// TI - Acute, nongenomic actions of the neuroactive gonadal steroid, 3α-hydroxy-4-pregnen-20-one (3αHP), on FSH release in perifused rat anterior pituitary cells JO - Endocrine VL - 6 UR - https://doi.org/10.1007/BF02820496 DO - 10.1007/BF02820496 ID - Beck1997 ER - TY - JOUR AU - Lewis, M. J. AU - Wiebe, J. P. AU - Heathcote, J. G. PY - 2004 DA - 2004// TI - Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma JO - BMC Cancer VL - 4 UR - https://doi.org/10.1186/1471-2407-4-27 DO - 10.1186/1471-2407-4-27 ID - Lewis2004 ER - TY - JOUR AU - Abul-Hajj, Y. J. AU - Iverson, R. AU - Kiang, D. T. PY - 1979 DA - 1979// TI - Metabolism of pregnenolone by human breast cancer: evidence for 17alpha-hydroxylase and 17,20-lyase JO - Steroids VL - 34 UR - https://doi.org/10.1016/0039-128X(79)90094-1 DO - 10.1016/0039-128X(79)90094-1 ID - Abul-Hajj1979 ER - TY - JOUR AU - Gunasegaram, R. AU - Peh, K. L. AU - Loganath, A. AU - Ratnam, S. S. PY - 1998 DA - 1998// TI - Expression of 3β-hydroxysteroid dehydrogenase-5,4-en isomerase activity by infiltrating ductal human breast carcinoma in vitro JO - Breast Cancer Res Treat VL - 50 UR - https://doi.org/10.1023/A:1006009031839 DO - 10.1023/A:1006009031839 ID - Gunasegaram1998 ER - TY - JOUR AU - Sutherland, R. M. PY - 1988 DA - 1988// TI - Cell and environment interactions in tumor microregions: the multicell spheroid model JO - Science VL - 240 UR - https://doi.org/10.1126/science.2451290 DO - 10.1126/science.2451290 ID - Sutherland1988 ER - TY - JOUR AU - Kenny, P. A. AU - Bissell, M. J. PY - 2003 DA - 2003// TI - Tumor reversion: correction of malignant behavior by microenvironmental cues JO - Int J Cancer VL - 107 UR - https://doi.org/10.1002/ijc.11491 DO - 10.1002/ijc.11491 ID - Kenny2003 ER - TY - JOUR AU - Hayashi, S. -. I. AU - Yamaguchi, Y. PY - 2008 DA - 2008// TI - Estrogen signaling pathway and hormone therapy JO - Breast Cancer VL - 15 UR - https://doi.org/10.1007/s12282-008-0070-z DO - 10.1007/s12282-008-0070-z ID - Hayashi2008 ER - TY - JOUR AU - Hu, M. AU - Polyak, K. PY - 2008 DA - 2008// TI - Molecular characterization of the tumor microenvironment in breast cancer JO - Eur J Cancer VL - 44 UR - https://doi.org/10.1016/j.ejca.2008.09.038 DO - 10.1016/j.ejca.2008.09.038 ID - Hu2008 ER - TY - JOUR AU - Wilson, C. AU - Holen, I. AU - Coleman, R. E. PY - 2012 DA - 2012// TI - Seed, soil and secreted hormones: potential interactions by breast cancer cells with their endocrine/paracrine microenvironments and implications for treatment with bisphosphonates JO - Cancer Treat Rev VL - 38 UR - https://doi.org/10.1016/j.ctrv.2012.02.007 DO - 10.1016/j.ctrv.2012.02.007 ID - Wilson2012 ER - TY - CHAP AU - Fuqua, S. A. PY - 1992 DA - 1992// TI - Where is the lesion in hormone-independent breast cancer? BT - J Natl Cancer Inst ID - Fuqua1992 ER - TY - JOUR AU - Murphy, L. C. PY - 1998 DA - 1998// TI - Mechanisms of hormone independence in human breast cancer JO - In Vivo VL - 12 ID - Murphy1998 ER - TY - JOUR AU - Pawlak, K. J. AU - Wiebe, J. P. PY - 2007 DA - 2007// TI - Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites JO - J Steroid Biochem Mol Biol VL - 107 UR - https://doi.org/10.1016/j.jsbmb.2007.05.030 DO - 10.1016/j.jsbmb.2007.05.030 ID - Pawlak2007 ER -