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Table 3 Immunohistochemical description of the MA and BL tumors groups (%).

From: Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15

 

Molecular apocrine

Basal-like

P-value

No. patients

58

13

 

ER(-)

54 (93)

13 (100)

>0.99

PR(-)

56 (97)

13 (100)

>0.99

HER2(3+)

39 (67)

0 (0)

<0.0001

GCDFP15(+)

33 (57)

0 (0)

<0.0001

AR(+)

33 (58)

0 (0)

<0.0001

FOXA1(+)

52 (90)

4 (31)

<0.0001

EGFR(-)

40 (70)

4 (31)

0.012

CK5/6(-)

51 (89)

5 (38)

0.0003

CK17(-)

54 (95)

5 (38)

<0.0001

Ki67 median (range of % stained cells)

30 (0 to 80)

50 (0 to 90)

0.27

  1. AR, androgen receptor; BL, basal-like; ER, estrogen receptor; HER2, Human Epidermal Growth Factor Receptor 2; MA, molecular apocrine; PR, progesterone receptor.