Table 2 Molecular characteristics of the MA and BL tumors groups (%)
Molecular apocrine | Basal-like | P-value | |
|---|---|---|---|
No. patients | 58 | 13 | |
ER expression (mRNA) (pos >20) -negative | 58 (100) | 13 (100) | >0.99 |
HER2 expression (mRNA) (pos >7) -positive -negative -nd | 38 (68) 18 (32) 2 | 0 (0) 13 (100) 0 | <0.0001 |
AR expression (mRNA) (pos >100) -positive -negative | 58 (100) 0 (0) | 2 (15) 11 (85) | <0.0001 |
FOXA1 expression (mRNA) (pos >100) -positive -negative | 58 (100) 0 (0) | 0 (0) 13 (100) | <0.0001 |
PIK3CA status: -wild type -mutated - exon 9: E542K and E545K - exon 20: H1047R | 47 (81) 11 (19) 1 10 | 13 (100) 0 0 0 | 0.20 |
TP53 status (FASAY test) -functional -nonfunctional | 29 (50) 29 (50) | 0 (0) 13 (100) | 0.0005 |