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Figure 4 | Breast Cancer Research

Figure 4

From: miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs

Figure 4

Differential expression of miRNAs with respect to E-cadherin status. Differentially expressed miRNAs (A) between E-cadherin mutant and wild-type breast cancer cell lines in the luminal-group, and (B) between E-cadherin promoter hypermethylated and wild-type breast cancer cell lines in the estrogen receptor-negative/basal group. Cell lines HCC1806, SK-BR-7, SUM102PT, SUM149PT, and SUM229PE, which show partial promoter hypermethylation, were not included in the analysis since we were not sure to which extent partial promoter methylation will affect E-cadherin expression levels in these cell lines. Yellow and blue, high and low overall similarity of samples in miRNA expression, respectively.

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