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Figure 1 | Breast Cancer Research

Figure 1

From: miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs

Figure 1

Molecular subtyping of 51 human breast cancer cell lines. Pearson correlation plot based on global mRNA expression of the top 10% variable genes. Breast cancer cell lines are depicted according to their overall similarity in gene expression. Yellow and blue, high and low overall similarity of samples in mRNA expression, respectively. Two main groups of 27 and 23 cell lines were apparent. Color codes for breast cancer subtypes based on intrinsic gene set: green, luminal-type cell lines; brown, luminal ERBB2-positive cell lines; black, normal-like/claudin-low cell lines; orange, basal-like cell lines; blue, estrogen receptor (ER)-negative/ERBB2-positive cell lines; pink, other subtype cell lines.

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