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Figure 1 | Breast Cancer Research

Figure 1

From: Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer

Figure 1

GOBO analyses of QSOX1 transcript expression among subtypes of breast cancer from over 1,800 cases. a) Box plot analysis of QSOX1 mRNA expression in all tumors ER+ (n = 1,225) and ER- tumors (n = 395) (P < 0.00001); b) Box plot analyses of QSOX1 expression among HU subtypes, Basal (n = 357), HER2 (n = 152), Luminal A (n = 482), Luminal B (n = 289), Normal-like (n = 257) and unclassified (n = 344), (P < 0.00001). c) Kaplan Meier analysis over 10 years of relapse free survival (RFS) in patients with Luminal B breast cancer expressing high (red line) and low (gray line) QSOX1 mRNA; High (n = 56), low (n = 74), (P = 0.00062) and d) Overall survival (OS); High (n = 34), low (n = 64), (P = 0.00031). Data obtained using GOBO, Gene expression based Outcome for Breast cancer Online.

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Breast Cancer Research

ISSN: 1465-542X

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