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Table 2 Distributions of tumor characteristics for categories of HOXB13:IL17BR, MGI, and MGI+HOXB13:IL17BR, and BCI.

From: HOXB13:IL17BR and molecular grade index and risk of breast cancer death among patients with lymph node-negative invasive disease

  HOXB13:IL17BR MGI MGI+HOXB13:IL17BR BCI  
  Low
(n = 293)
High
(n = 315)
Low
(n = 248)
High
(n = 360)
Low
(n = 248)
Intermediate
(n = 158)
High
(n = 202)
Low
(n = 277)
Intermediate
(n = 139)
High
(n = 192)
Total
(n = 608)
Tumor size (cm)           
   ≤ 1.0 97 (58%) 71 (42%) 91 (54%) 77 (46%) 91 (54%) 39 (23%) 38 (23%) 96 (57%) 37 (22%) 35 (21%) 168
   1.1 - 2.0 130 (48%) 141 (52%) 105 (39%) 166 (61%) 105 (39%) 77 (28%) 89 (33%) 119 (44%) 62 (23%) 90 (33%) 271
   >2.0 66 (39%) 103 (61%) 52 (31%) 117 (69%) 52 (31%) 42 (25%) 75 (44%) 62 (37%) 40 (24%) 67 (40%) 169
Tumor grade1            
   Well 95 (66%) 49 (34%) 103 (72%) 41 (28%) 103 (72%) 24 (17%) 17 (12%) 106 (74%) 29 (20%) 9 (6%) 144
   Moderate 133 (51%) 128 (49%) 134 (51%) 127 (49%) 134 (51%) 73 (28%) 54 (21%) 144 (55%) 68 (26%) 49 (19%) 261
   Poor 65 (32%) 138 (68%) 11 (5%) 192 (95%) 11 (5%) 61 (30%) 131 (65%) 27 (13%) 42 (21%) 134 (66%) 203
Tumor size and grade2           
   Group 1 129 (66%) 66 (34%) 129 (66%) 66 (34%) 129 (66%) 42 (22%) 24 (12%) 134 (69%) 45 (23%) 16 (8%) 195
   Group 2 106 (40%) 156 (60%) 80 (31%) 182 (69%) 80 (31%) 76 (29%) 106 (40%) 93 (36%) 60 (23%) 109 (42%) 262
   Group 3 58 (38%) 93 (62%) 39 (26%) 112 (74%) 39 (26%) 40 (26%) 72 (48%) 50 (33%) 34 (23%) 67 (44%) 151
ER status            
   Positive 274 (53%) 241 (47%) 237 (46%) 278 (54%) 237 (46%) 140 (27%) 138 (27%) 259 (50%) 119 (23%) 137 (27%) 515
   Negative 19 (20%) 74 (80%) 11 (12%) 82 (88%) 11 (12%) 18 (19%) 64 (69%) 18 (19%) 20 (22%) 55 (59%) 93
PR status            
   Positive 257 (58%) 184 (42%) 211 (48%) 230 (52%) 211 (48%) 126 (29%) 104 (24%) 239 (54%) 99 (22%) 103 (23%) 441
   Negative 36 (22%) 131 (78%) 37 (22%) 130 (78%) 37 (22%) 23 (19%) 98 (59%) 38 (23%) 40 (24%) 89 (53%) 167
HER2 status            
   Positive 12 (16%) 62 (84%) 16 (22%) 58 (78%) 16 (22%) 11 (15%) 47 (64%) 23 (31%) 16 (22%) 35 (47%) 74
   Negative 281 (53%) 253 (47%) 232 (43%) 302 (57%) 232 (43%) 147 (28%) 155 (29%) 254 (48%) 123 (23%) 157 (29%) 534
  1. 1As determined by pathologist 1; 2Group 1 (≤ 2.0 cm and well or ≤ 1.0 cm and moderate); Group 2 (>2.0 cm and well, or 1.1 to 2.0 cm and moderate, or ≤ 2.0 cm and poor); Group 3 (>2.0 cm and moderate/poor).