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Table 2 Association between high BiP mRNA levels and PrP mRNA levels

From: Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer

  

Low BiP

High BiP

P-

n

Reference

  

Mean ± SD

Mean ± SD

value

  
 

BiP

0.80 ± 0.1

1.29 ± 0.3

≤0.001*

127

van der Vijver et al., 2002

 

PrP

1.01 ± 0.5

1.24 ± 0.7

0.002*

  

Breast cancer

BiP

0.78 ± 0.1

1.26 ± 0.3

≤0.001*

44

Minn et al., 2005

 

PrP

0.93 ± 0.4

1.09 ± 0.5

0.1

  
 

BiP

0.76 ± 0.2

1.43 ± 0.4

≤0.001*

40

Chin et al., 2006

 

PrP

1.00 ± 0.5

1.38 ± 0.6

0.003*

  

Breast carcinoma

BiP

0.77 ± 0.2

1.37 ± 0.4

≤0.001*

56

Neve et al., 2006

cell lines

PrP

0.99 ± 0.9

1.94 ± 1.0

0.001*

 Â