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Table 2 Association between high BiP mRNA levels and PrP mRNA levels

From: Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer

   Low BiP High BiP P- n Reference
   Mean ± SD Mean ± SD value   
  BiP 0.80 ± 0.1 1.29 ± 0.3 ≤0.001* 127 van der Vijver et al., 2002
  PrP 1.01 ± 0.5 1.24 ± 0.7 0.002*   
Breast cancer BiP 0.78 ± 0.1 1.26 ± 0.3 ≤0.001* 44 Minn et al., 2005
  PrP 0.93 ± 0.4 1.09 ± 0.5 0.1   
  BiP 0.76 ± 0.2 1.43 ± 0.4 ≤0.001* 40 Chin et al., 2006
  PrP 1.00 ± 0.5 1.38 ± 0.6 0.003*   
Breast carcinoma BiP 0.77 ± 0.2 1.37 ± 0.4 ≤0.001* 56 Neve et al., 2006
cell lines PrP 0.99 ± 0.9 1.94 ± 1.0 0.001*