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Table 3 Correlation between diffuse optical spectroscopic imaging parameters andfibroglandular density measured with magnetic resonance imaging for subjects atbaseline and at time points during chemotherapy

From: Optical imaging correlates with magnetic resonance imaging breast density and revealscomposition changes during neoadjuvant chemotherapy

 

Baseline (n= 12)

~25 days (n= 10)

Mean, 24.8 ± 5.5

~82 days (n= 7)

Mean, 82.4 ± 11.9

 

R

P

R

P

r

P

Water

0.843

<0.001

0.675

0.032

0.405

0.367

Lipid

-0.707

0.010

-0.462

0.179

-0.018

0.970

ctO2Hb

0.557

0.060

0.647

0.043

0.464

0.294

ctHHb

0.785

0.003

0.399

0.253

0.705

0.077

ctTHb

0.597

0.040

0.644

0.045

0.599

0.155

stO2

0.196

0.543

0.240

0.505

0.012

0.979

TOI

0.891

<0.001

0.541

0.107

0.593

0.160

Scat. power

0.205

0.523

0.143

0.694

0.265

0.566

  1. Bold values indicate statistical significance at the 0.05 level.ctO2Hb, oxyhemoglobin concentration; ctHHb, deoxyhemoglobinconcentration; ctTHb, total hemoglobin concentration; stO2, tissueoxygen saturation; TOI, tissue optical index; Scat. power, optical scatteringpower.