Figure 7From: Optical imaging correlates with magnetic resonance imaging breast density and revealscomposition changes during neoadjuvant chemotherapyCorresponding magnetic resonance imaging (MRI) and diffuse opticalspectroscopic imaging (DOSI). Images were taken at baseline and end ofneoadjuvant chemotherapy in the contralateral normal breast of a premenopausalpatient. The yellow outlines in the MRI images depict the result of thesegmentation algorithm for fibroglandular tissue in the shown slices. The DOSImaps depict measured parameters as a function of position (tick mark separationequals 1 cm). The illustrated maps are from an 8- × 6-cm area from theupper-inner region of the left breast. The areolar region has more water,outlined by the semicircle. The decreased density after chemotherapy is clearlyvisible in both MRI and DOSI. MRI shows 30.4% reduction in fibroglandulartissue volume, and DOSI shows 24.4% reduction in tissue water. ctHHb,deoxyhemoglobin concentration; TOI, tissue optical index.Back to article page