Sensitivity in breast cancer | Specificity in healthy controls | Specificity in benign breast diseases | ||||
---|---|---|---|---|---|---|
Gene | Methylation positive | % | Methylation negative | % | Methylation negative | % |
ITIH5 | 27 of 112 | 24 | 96 of 102 | 94 | 20 of 20 | 100 |
DKK3 | 37 of 112 | 33 | 101 of 102 | 99 | 20 of 20 | 100 |
WIF1 | 39 of 112 | 35 | 97 of 102 | 95 | 15 of 20 | 75 |
SFRP1 | 12 of 112 | 11 | 92 of 102 | 90 | 17 of 20 | 85 |
SFRP2 | 21 of 112 | 19 | 90 of 102 | 88 | 18 of 20 | 90 |
SFRP5 | 9 of 112 | 8 | n.d. | n.d. | ||
DKK3/ITIH5 a | 46 of 112 | 41 | 95 of 102 | 93 | 20 of 20 | 100 |