Skip to main content
Figure 8 | Breast Cancer Research

Figure 8

From: Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors

Figure 8

Positive estrogen receptor status in breast tumors significantly associated with lower levels of TrxR1 expression. (A) TrxR1, estrogen receptor (ER) and p53 expression was analyzed by immunohistochemistry (IHC) in a panel of 57 (36 ER-, 21 ER+) breast tumors. Representative images from IHC and hematoxylin and eosin (HE) staining of ER-/p53+ (row 1), ER-/p53- (row 2), ER+/p53- (rows 3 and 4) and ER+/p53+ (row 5) breast tumors. Original magnification: 20 ×. (C) TrxR1 (IHC) scoring in ER- and ER+ tumors. (D) TrxR1 (IHC) scoring in p53- and p53+ breast tumors. TrxR, thioredoxin reductase.

Back to article page