Breast Cancer Research

Table 3 Parameter definitions for base-case and sensitivity analyses of overdiagnosismodel.

From: Modelling the overdiagnosis of breast cancer due to mammography screening in womenaged 40 to 49 in the United Kingdom

	Screening test		Mean sojourn time (years)
	sensitivity (%)		40 to 49			50-59
Invasive	Invasive	In-situ	NPIS	PIS	PIBC	NPIS	PIS	PIBC
Base case	Median¹		Median			3	0.175	1.825
Long MST	Median		Upper limit²			5	0.25	2.75
Short MST	Median		Lower limit³			2	0.1	1.5
High sensitivity	100	100	Median			3	0.175	1.825
Low sensitivity	Lower limit		Median			3	0.175	1.825
Low sensitivity, long MST	Lower limit		Upper limit			5	0.25	2.75
High sensitivity, long MST	100	100	Upper limit			5	0.25	2.75

^1,2,3Refers to the median, upper limit, and lower limit of resultsfrom parameter estimation model, respectively. MST, median sojourn time; NPIC,non-progressive in situ; PIBC, preclinical invasive breast cancer; PIS,preclinical progressive in situ.

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