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Figure 7 | Breast Cancer Research

Figure 7

From: A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications

Figure 7

Haploblocks within the complex genomic region (chr17: 36,350,000-36,750,000 in hg18). (A) Linkage disequilibrium between the deletion polymorphism (rs72137527) and HapMap single-nucleotide polymorphisms (SNPs). The r2 values between the rs72137527 and each HapMap SNP are plotted against the physical locations of each SNP. (B) Haploblocks for the entire complex region. Triangular plots were generated by using Haploview for the HapMap SNP genotypes from three major populations (release 28) and are shown each for a centromeric half and a telomeric half. Red, strong linkage; white, no linkage.

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