Skip to main content
Figure 5 | Breast Cancer Research

Figure 5

From: A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications

Figure 5

Recurrent duplications of genomic segments within the complex region during primate evolution. (A) A pie chart showing the proportion of duplications within the complex region, duplications between the complex region and outside of the region in the same chromosome, and duplications between the complex region and different chromosomes (interchromosomal duplications). Intrachromosomal duplications within the complex region account for three fourths of all the duplications. (B) Duplications within the complex region are binned based on size (x-axis), and the number of duplications for each bin is shown in the bar graph. A unique color is given based on the sequence identity between duplicated segments. (C) Inferred duplication activities within the complex region. Duplications are binned into four groups based on the sequence identity between duplicated segments, and older duplications (duplications with lower sequence identities) are overlaid by the newer duplications (duplications with higher sequence identities).

Back to article page