Laser-capture microdissection (LCM) of breast cancer cells. Malignant mammary epithelial cells were isolated from primary breast tumors (top panels) and bone trephines (bottom panels). The selected regions containing the breast cancer cells were adhered to LCM caps (right panels). Left panels represent images of slides after completion of LCM, with black arrows indicating the isolated material. The scale bar on the top left image represents 1,000 μm and applies to all panels.