Manchester Scoring method | Cohort, n | Total BRCA1 carriers, n | No pathology adjustment | With pathology adjustment | ||
---|---|---|---|---|---|---|
 |  |  | Individuals tested, n | BRCA1carriers tested, n | Individuals tested, n | BRCA1carriers tested, n |
Adjustment + estrogen-receptor status | 345 | 28 | 72 | 12 | 82 | 18 |
Adjustment + estrogen-receptor + PTEN status | 26 | 7 | 5 | 3 | 10 | 6 |