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Table 4 Overall number of carriers for each predicted range of probability of being a BRCA1 or a BRCA2 carrier

From: Triple-negative breast cancer and PTEN (phosphatase and tensin homologue)loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer

Overall score

Number of women

Number of carriers

Percentage of carriers

≤3.5

25

0

0

-3.0 to -3.5

49

2

4

-2.5 to -3.0

47

2

4

-2.0 to -2.5

144

13

9

-1.5 to -2.0

58

8

14

-1.0 to -1.5

59

17

29

0 to -1.0

33

11

33

0 to 1

16

12

75

  1. The number of carriers for each predicted range of probability calculated through incorporation of logistic regression coefficients generated in Table 3.