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Table 4 Overall number of carriers for each predicted range of probability of being a BRCA1 or a BRCA2 carrier

From: Triple-negative breast cancer and PTEN (phosphatase and tensin homologue)loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer

Overall score Number of women Number of carriers Percentage of carriers
≤3.5 25 0 0
-3.0 to -3.5 49 2 4
-2.5 to -3.0 47 2 4
-2.0 to -2.5 144 13 9
-1.5 to -2.0 58 8 14
-1.0 to -1.5 59 17 29
0 to -1.0 33 11 33
0 to 1 16 12 75
  1. The number of carriers for each predicted range of probability calculated through incorporation of logistic regression coefficients generated in Table 3.