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Table 2 Correlation of clinicopathologic characterestics and VEGFR1 mRNA expression

From: Vascular endothelial growth factor receptor-1 mRNA overexpression in peripheral blood as a useful prognostic marker in breast cancer

  VEGFR1mRNA in peripheral blood
  negative Positive  
  (n = 466) (n = 49)  
Factors No. % No. % P
Age (mean ± SD) 55.5 ± 11.5 54.5 ± 11.5 0.66
Tumor size      
   small (Tis to T1) 189 40.6 13 26.5 <0.05
   large (T2 to T4) 277 59.4 36 73.5  
Lymphnode metastasis      
   negative 316 67.8 26 53.1 <0.05
   positive 150 32.2 23 46.9  
Lymphatic involvement      
   negative 289 62.0 27 55.1 0.34
   positive 177 38.0 22 44.9  
Vascular involvement      
   negative 438 94.0 43 87.8 0.09
   positive 28 6.0 6 12.2  
Nuclear grade      
   I/II 311 66.7 35 71.4 0.50
   III 155 33.3 14 28.6  
Hormone receptor      
   negative 112 24.0 11 22.4 0.80
   positive 354 76.0 38 77.6  
HER-2/NEU      
   negative 301 86.0 18 94.7 0.23
   positive 49 14.0 1 5.3  
CEA      
   <5.0 408 94.9 44 95.7 0.82
   >5.1 22 5.1 2 4.3  
Stage      
   0 6 1.3 0 0.0 <0.01
   I 143 30.7 12 24.5  
   II 290 62.2 26 53.1  
   III 27 5.8 11 22.4  
Recurrence      
   negative 404 86.7 34 69.4 <0.01
   positive 62 13.3 15 30.6  
Prognosis      
   alive 449 96.4 39 79.6 <0.0001
   dead 17 3.6 10 20.4  
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