| |
VEGFR1mRNA in peripheral blood
|
|---|
| |
negative
|
Positive
| |
|---|
| |
(n = 466)
|
(n = 49)
| |
|---|
|
Factors
|
No.
|
%
|
No.
|
%
|
P
|
|---|
|
Age (mean ± SD)
|
55.5 ± 11.5
|
54.5 ± 11.5
|
0.66
|
|
Tumor size
| | | | | |
|
small (Tis to T1)
|
189
|
40.6
|
13
|
26.5
|
<0.05
|
|
large (T2 to T4)
|
277
|
59.4
|
36
|
73.5
| |
|
Lymphnode metastasis
| | | | | |
|
negative
|
316
|
67.8
|
26
|
53.1
|
<0.05
|
|
positive
|
150
|
32.2
|
23
|
46.9
| |
|
Lymphatic involvement
| | | | | |
|
negative
|
289
|
62.0
|
27
|
55.1
|
0.34
|
|
positive
|
177
|
38.0
|
22
|
44.9
| |
|
Vascular involvement
| | | | | |
|
negative
|
438
|
94.0
|
43
|
87.8
|
0.09
|
|
positive
|
28
|
6.0
|
6
|
12.2
| |
|
Nuclear grade
| | | | | |
|
I/II
|
311
|
66.7
|
35
|
71.4
|
0.50
|
|
III
|
155
|
33.3
|
14
|
28.6
| |
|
Hormone receptor
| | | | | |
|
negative
|
112
|
24.0
|
11
|
22.4
|
0.80
|
|
positive
|
354
|
76.0
|
38
|
77.6
| |
|
HER-2/NEU
| | | | | |
|
negative
|
301
|
86.0
|
18
|
94.7
|
0.23
|
|
positive
|
49
|
14.0
|
1
|
5.3
| |
|
CEA
| | | | | |
|
<5.0
|
408
|
94.9
|
44
|
95.7
|
0.82
|
|
>5.1
|
22
|
5.1
|
2
|
4.3
| |
|
Stage
| | | | | |
|
0
|
6
|
1.3
|
0
|
0.0
|
<0.01
|
|
I
|
143
|
30.7
|
12
|
24.5
| |
|
II
|
290
|
62.2
|
26
|
53.1
| |
|
III
|
27
|
5.8
|
11
|
22.4
| |
|
Recurrence
| | | | | |
|
negative
|
404
|
86.7
|
34
|
69.4
|
<0.01
|
|
positive
|
62
|
13.3
|
15
|
30.6
| |
|
Prognosis
| | | | | |
|
alive
|
449
|
96.4
|
39
|
79.6
|
<0.0001
|
|
dead
|
17
|
3.6
|
10
|
20.4
| |
