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Table 4 Five-year survival estimates by expression levels of translational regulators.

From: Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer

  

N

Events

Five-year estimate

95% CI

Pvalue

RFS

      

p4E-BP1 S65

High

8

7

37.5%

(15.3%, 91.7%)

 
 

Low

180

40

88.7%

(83.9%, 93.8%)

<0.0001

OS

      

pS6 S235/236

High

11

6

52.6%

(26.1%, 100%)

 
 

Low

177

59

87.9%

(82.7%, 88.8%)

0.0001

eEF2K

High

126

51

79.0%

(71.8%, 86.9%)

 
 

Low

62

14

85.9%

(77.3%, 95.5%)

0.0424

Pdcd4

High

78

16

91.5%

(85.2%, 98.3%)

 
 

Low

110

49

74.2%

(66.2%, 83.4%)

0.0021

  1. CI, confidence interval; OS, overall survival; RFS, recurrence-free survival.